MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA
Identifieur interne : 000D14 ( Main/Exploration ); précédent : 000D13; suivant : 000D15MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA
Auteurs : Yutaka Terada [Japon] ; Kengo Kawachi [Japon] ; Yoshiharu Matsuura [Japon] ; Wataru Kamitani [Japon]Source :
- Virology [ 0042-6822 ] ; 2017.
Descripteurs français
- KwdFr :
- ARN viral (métabolisme), Analyse de mutations d'ADN, Coronavirus du syndrome respiratoire du Moyen-Orient (physiologie), Génétique inverse, Humains, Lignée cellulaire, Protéines mutantes (génétique), Protéines mutantes (métabolisme), Protéines virales non structurales (génétique), Protéines virales non structurales (métabolisme), Réplication virale.
- MESH :
- génétique : Protéines mutantes, Protéines virales non structurales.
- métabolisme : ARN viral, Protéines mutantes, Protéines virales non structurales.
- physiologie : Coronavirus du syndrome respiratoire du Moyen-Orient.
- Analyse de mutations d'ADN, Génétique inverse, Humains, Lignée cellulaire, Réplication virale.
English descriptors
- KwdEn :
- Cell Line, DNA Mutational Analysis, Humans, Middle East Respiratory Syndrome Coronavirus (physiology), Mutant Proteins (genetics), Mutant Proteins (metabolism), RNA, Viral (metabolism), Reverse Genetics, Viral Nonstructural Proteins (genetics), Viral Nonstructural Proteins (metabolism), Virus Replication.
- MESH :
- chemical , genetics : Mutant Proteins, Viral Nonstructural Proteins.
- chemical , metabolism : Mutant Proteins, RNA, Viral, Viral Nonstructural Proteins.
- physiology : Middle East Respiratory Syndrome Coronavirus.
- Cell Line, DNA Mutational Analysis, Humans, Reverse Genetics, Virus Replication.
Abstract
MERS-CoV is the only lethal human CoV still endemic in the Arabian Peninsula and neither vaccine nor therapeutics against MERS-CoV infection is available. The nsp1 of CoV is thought to be a major virulence factor because it suppresses protein synthesis through the degradation of host mRNA. In contrast, viral RNA circumvents the nsp1-mediated translational shutoff for an efficient propagation. In this study, we identified amino acid residue in MERS-CoV nsp1 that differ from those of SARS-CoV nsp1, and that appear to be crucial for circumventing the translational shutoff. In addition, reverse genetics analysis suggested the presence of a
Url:
DOI: 10.1016/j.virol.2017.08.026
PubMed: 28843094
PubMed Central: 7118922
Affiliations:
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Le document en format XML
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xml:lang="en" level="a" type="main">MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA</title><author><name sortKey="Terada, Yutaka" sort="Terada, Yutaka" uniqKey="Terada Y" first="Yutaka" last="Terada">Yutaka Terada</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Laboratory of Clinical Research on Infectious Diseases, Osaka University, Osaka 565-0871, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Clinical Research on Infectious Diseases, Osaka University, Osaka 565-0871</wicri:regionArea><wicri:noRegion>Osaka 565-0871</wicri:noRegion></affiliation></author><author><name sortKey="Kawachi, Kengo" sort="Kawachi, Kengo" uniqKey="Kawachi K" first="Kengo" last="Kawachi">Kengo Kawachi</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Laboratory of Clinical Research on Infectious Diseases, Osaka University, Osaka 565-0871, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Clinical Research on Infectious Diseases, Osaka University, Osaka 565-0871</wicri:regionArea><wicri:noRegion>Osaka 565-0871</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff0010">Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871</wicri:regionArea><wicri:noRegion>Osaka 565-0871</wicri:noRegion></affiliation></author><author><name sortKey="Matsuura, Yoshiharu" sort="Matsuura, Yoshiharu" uniqKey="Matsuura Y" first="Yoshiharu" last="Matsuura">Yoshiharu Matsuura</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871</wicri:regionArea><wicri:noRegion>Osaka 565-0871</wicri:noRegion></affiliation></author><author><name sortKey="Kamitani, Wataru" sort="Kamitani, Wataru" uniqKey="Kamitani W" first="Wataru" last="Kamitani">Wataru Kamitani</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Laboratory of Clinical Research on Infectious Diseases, Osaka University, Osaka 565-0871, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Clinical Research on Infectious Diseases, Osaka University, Osaka 565-0871</wicri:regionArea><wicri:noRegion>Osaka 565-0871</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff0015">Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba, Ibaraki 305-0843, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba, Ibaraki 305-0843</wicri:regionArea><wicri:noRegion>Ibaraki 305-0843</wicri:noRegion></affiliation></author></analytic><series><title level="j">Virology</title><idno type="ISSN">0042-6822</idno><idno type="eISSN">1096-0341</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cell Line</term><term>DNA Mutational Analysis</term><term>Humans</term><term>Middle East Respiratory Syndrome Coronavirus (physiology)</term><term>Mutant Proteins (genetics)</term><term>Mutant Proteins (metabolism)</term><term>RNA, Viral (metabolism)</term><term>Reverse Genetics</term><term>Viral Nonstructural Proteins (genetics)</term><term>Viral Nonstructural Proteins (metabolism)</term><term>Virus Replication</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (métabolisme)</term><term>Analyse de mutations d'ADN</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (physiologie)</term><term>Génétique inverse</term><term>Humains</term><term>Lignée cellulaire</term><term>Protéines mutantes (génétique)</term><term>Protéines mutantes (métabolisme)</term><term>Protéines virales non structurales (génétique)</term><term>Protéines virales non structurales (métabolisme)</term><term>Réplication virale</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Mutant Proteins</term><term>Viral Nonstructural Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Mutant Proteins</term><term>RNA, Viral</term><term>Viral Nonstructural Proteins</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines mutantes</term><term>Protéines virales non structurales</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>ARN viral</term><term>Protéines mutantes</term><term>Protéines virales non structurales</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cell Line</term><term>DNA Mutational Analysis</term><term>Humans</term><term>Reverse Genetics</term><term>Virus Replication</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de mutations d'ADN</term><term>Génétique inverse</term><term>Humains</term><term>Lignée cellulaire</term><term>Réplication virale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>MERS-CoV is the only lethal human CoV still endemic in the Arabian Peninsula and neither vaccine nor therapeutics against MERS-CoV infection is available. The nsp1 of CoV is thought to be a major virulence factor because it suppresses protein synthesis through the degradation of host mRNA. In contrast, viral RNA circumvents the nsp1-mediated translational shutoff for an efficient propagation. In this study, we identified amino acid residue in MERS-CoV nsp1 that differ from those of SARS-CoV nsp1, and that appear to be crucial for circumventing the translational shutoff. In addition, reverse genetics analysis suggested the presence of a <italic>cis</italic>-acting element at the 5′-terminus of the nsp1-coding region, which contributes to the specific recognition of viral RNA that is required for an efficient viral replication. Our results suggest the CoVs share a common mechanism for circumventing the nsp1-mediated translational shutoff.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Almazan, F" uniqKey="Almazan F">F. Almazán</name></author><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. Dediego</name></author><author><name sortKey="Galan, C" uniqKey="Galan C">C. Galán</name></author><author><name sortKey="Escors, D" uniqKey="Escors D">D. Escors</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Álvarez</name></author><author><name sortKey="Ortego, J" uniqKey="Ortego J">J. Ortego</name></author><author><name sortKey="Sola, I" uniqKey="Sola I">I. Sola</name></author><author><name sortKey="Zu Iga, S" uniqKey="Zu Iga S">S. Zuñiga</name></author><author><name sortKey="Alonso, S" uniqKey="Alonso S">S. Alonso</name></author><author><name sortKey="Moreno, J L" uniqKey="Moreno J">J.L. Moreno</name></author><author><name sortKey="Nogales, A" uniqKey="Nogales A">A. Nogales</name></author><author><name sortKey="Capiscol, C" uniqKey="Capiscol C">C. Capiscol</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almazan, F" uniqKey="Almazan F">F. Almazán</name></author><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. DeDiego</name></author><author><name sortKey="Sola, I" uniqKey="Sola I">I. Sola</name></author><author><name sortKey="Zu Iga, S" uniqKey="Zu Iga S">S. Zuñiga</name></author><author><name sortKey="Nieto Torres, J L" uniqKey="Nieto Torres J">J.L. Nieto-Torres</name></author><author><name sortKey="Marquez Jurado, S" uniqKey="Marquez Jurado S">S. Marquez-Jurado</name></author><author><name sortKey="Andres, G" uniqKey="Andres G">G. Andrés</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almeida, M S" uniqKey="Almeida M">M.S. Almeida</name></author><author><name sortKey="Johnson, M A" uniqKey="Johnson M">M.A. Johnson</name></author><author><name sortKey="Herrmann, T" uniqKey="Herrmann T">T. Herrmann</name></author><author><name sortKey="Geralt, M" uniqKey="Geralt M">M. Geralt</name></author><author><name sortKey="Wuthrich, K" uniqKey="Wuthrich K">K. Wüthrich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bermingham, A" uniqKey="Bermingham A">A. Bermingham</name></author><author><name sortKey="Chand, M A" uniqKey="Chand M">M.A. Chand</name></author><author><name sortKey="Brown, C S" uniqKey="Brown C">C.S. Brown</name></author><author><name sortKey="Aarons, E" uniqKey="Aarons E">E. Aarons</name></author><author><name sortKey="Tong, C" uniqKey="Tong C">C. Tong</name></author><author><name sortKey="Langrish, C" uniqKey="Langrish C">C. Langrish</name></author><author><name sortKey="Hoschler, K" uniqKey="Hoschler K">K. Hoschler</name></author><author><name sortKey="Brown, K" uniqKey="Brown K">K. Brown</name></author><author><name sortKey="Galiano, M" uniqKey="Galiano M">M. Galiano</name></author><author><name sortKey="Myers, R" uniqKey="Myers R">R. Myers</name></author><author><name sortKey="Pebody, R G" uniqKey="Pebody R">R.G. Pebody</name></author><author><name sortKey="Green, H K" uniqKey="Green H">H.K. Green</name></author><author><name sortKey="Boddington, N L" uniqKey="Boddington N">N.L. Boddington</name></author><author><name sortKey="Gopal, R" uniqKey="Gopal R">R. Gopal</name></author><author><name sortKey="Price, N" uniqKey="Price N">N. Price</name></author><author><name sortKey="Newsholme, W" uniqKey="Newsholme W">W. Newsholme</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Zambon, M" uniqKey="Zambon M">M. Zambon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bradburne, A F" uniqKey="Bradburne A">A.F. Bradburne</name></author><author><name sortKey="Bynoe, M L" uniqKey="Bynoe M">M.L. Bynoe</name></author><author><name sortKey="Tyrrell, D A" uniqKey="Tyrrell D">D.A. Tyrrell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brockway, S M" uniqKey="Brockway S">S.M. Brockway</name></author><author><name sortKey="Denison, M R" uniqKey="Denison M">M.R. Denison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brockway, S M" uniqKey="Brockway S">S.M. Brockway</name></author><author><name sortKey="Lu, X T" uniqKey="Lu X">X.T. Lu</name></author><author><name sortKey="Peters, T R" uniqKey="Peters T">T.R. Peters</name></author><author><name sortKey="Dermody, T S" uniqKey="Dermody T">T.S. Dermody</name></author><author><name sortKey="Denison, M R" uniqKey="Denison M">M.R. Denison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, C G" uniqKey="Brown C">C.G. Brown</name></author><author><name sortKey="Nixon, K S" uniqKey="Nixon K">K.S. Nixon</name></author><author><name sortKey="Senanayake, S D" uniqKey="Senanayake S">S.D. Senanayake</name></author><author><name sortKey="Brian, D A" uniqKey="Brian D">D.A. Brian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buchan, D W" uniqKey="Buchan D">D.W. Buchan</name></author><author><name sortKey="Minneci, F" uniqKey="Minneci F">F. Minneci</name></author><author><name sortKey="Nugent, T C" uniqKey="Nugent T">T.C. Nugent</name></author><author><name sortKey="Bryson, K" uniqKey="Bryson K">K. Bryson</name></author><author><name sortKey="Jones, D T" uniqKey="Jones D">D.T. Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buchholz, U" uniqKey="Buchholz U">U. Buchholz</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Müller</name></author><author><name sortKey="Nitsche, A" uniqKey="Nitsche A">A. Nitsche</name></author><author><name sortKey="Sanewski, A" uniqKey="Sanewski A">A. Sanewski</name></author><author><name sortKey="Wevering, N" uniqKey="Wevering N">N. Wevering</name></author><author><name sortKey="Bauer Balci, T" uniqKey="Bauer Balci T">T. Bauer-Balci</name></author><author><name sortKey="Bonin, F" uniqKey="Bonin F">F. Bonin</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Schweiger, B" uniqKey="Schweiger B">B. Schweiger</name></author><author><name sortKey="Wolff, T" uniqKey="Wolff T">T. Wolff</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Buda, S" uniqKey="Buda S">S. Buda</name></author><author><name sortKey="Krause, G" uniqKey="Krause G">G. Krause</name></author><author><name sortKey="Schaade, L" uniqKey="Schaade L">L. Schaade</name></author><author><name sortKey="Haas, W" uniqKey="Haas W">W. Haas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cencic, R" uniqKey="Cencic R">R. Cencic</name></author><author><name sortKey="Desforges, M" uniqKey="Desforges M">M. Desforges</name></author><author><name sortKey="Hall, D R" uniqKey="Hall D">D.R. Hall</name></author><author><name sortKey="Kozakov, D" uniqKey="Kozakov D">D. Kozakov</name></author><author><name sortKey="Du, Y" uniqKey="Du Y">Y. Du</name></author><author><name sortKey="Min, J" uniqKey="Min J">J. Min</name></author><author><name sortKey="Dingledine, R" uniqKey="Dingledine R">R. Dingledine</name></author><author><name sortKey="Fu, H" uniqKey="Fu H">H. Fu</name></author><author><name sortKey="Vajda, S" uniqKey="Vajda S">S. Vajda</name></author><author><name sortKey="Talbot, P J" uniqKey="Talbot P">P.J. Talbot</name></author><author><name sortKey="Pelletier, J" uniqKey="Pelletier J">J. Pelletier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Channappanavar, R" uniqKey="Channappanavar R">R. Channappanavar</name></author><author><name sortKey="Fehr, A R" uniqKey="Fehr A">A.R. Fehr</name></author><author><name sortKey="Vijay, R" uniqKey="Vijay R">R. Vijay</name></author><author><name sortKey="Mack, M" uniqKey="Mack M">M. Mack</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Meyerholz, D K" uniqKey="Meyerholz D">D.K. Meyerholz</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, S C" uniqKey="Chen S">S.C. Chen</name></author><author><name sortKey="Olsthoorn, R C" uniqKey="Olsthoorn R">R.C. Olsthoorn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y. Chen</name></author><author><name sortKey="Su, C" uniqKey="Su C">C. Su</name></author><author><name sortKey="Ke, M" uniqKey="Ke M">M. Ke</name></author><author><name sortKey="Jin, X" uniqKey="Jin X">X. Jin</name></author><author><name sortKey="Xu, L" uniqKey="Xu L">L. Xu</name></author><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z. Zhang</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A. Wu</name></author><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y. Sun</name></author><author><name sortKey="Yang, Z" uniqKey="Yang Z">Z. Yang</name></author><author><name sortKey="Tien, P" uniqKey="Tien P">P. Tien</name></author><author><name sortKey="Ahola, T" uniqKey="Ahola T">T. Ahola</name></author><author><name sortKey="Liang, Y" uniqKey="Liang Y">Y. Liang</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X. Liu</name></author><author><name sortKey="Guo, D" uniqKey="Guo D">D. Guo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Connor, R F" uniqKey="Connor R">R.F. Connor</name></author><author><name sortKey="Roper, R L" uniqKey="Roper R">R.L. Roper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cowling, B J" uniqKey="Cowling B">B.J. Cowling</name></author><author><name sortKey="Park, M" uniqKey="Park M">M. Park</name></author><author><name sortKey="Fang, V J" uniqKey="Fang V">V.J. Fang</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P. Wu</name></author><author><name sortKey="Leung, G M" uniqKey="Leung G">G.M. Leung</name></author><author><name sortKey="Wu, J T" uniqKey="Wu J">J.T. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Decroly, E" uniqKey="Decroly E">E. Decroly</name></author><author><name sortKey="Debarnot, C" uniqKey="Debarnot C">C. Debarnot</name></author><author><name sortKey="Ferron, F" uniqKey="Ferron F">F. Ferron</name></author><author><name sortKey="Bouvet, M" uniqKey="Bouvet M">M. Bouvet</name></author><author><name sortKey="Coutard, B" uniqKey="Coutard B">B. Coutard</name></author><author><name sortKey="Imbert, I" uniqKey="Imbert I">I. Imbert</name></author><author><name sortKey="Gluais, L" uniqKey="Gluais L">L. Gluais</name></author><author><name sortKey="Papageorgiou, N" uniqKey="Papageorgiou N">N. Papageorgiou</name></author><author><name sortKey="Sharff, A" uniqKey="Sharff A">A. Sharff</name></author><author><name sortKey="Bricogne, G" uniqKey="Bricogne G">G. Bricogne</name></author><author><name sortKey="Ortiz Lombardia, M" uniqKey="Ortiz Lombardia M">M. Ortiz-Lombardia</name></author><author><name sortKey="Lescar, J" uniqKey="Lescar J">J. Lescar</name></author><author><name sortKey="Canard, B" uniqKey="Canard B">B. Canard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Gunther, S" uniqKey="Gunther S">S. Günther</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S. van der Werf</name></author><author><name sortKey="Brodt, H R" uniqKey="Brodt H">H.R. Brodt</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S. Becker</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H. Rabenau</name></author><author><name sortKey="Panning, M" uniqKey="Panning M">M. Panning</name></author><author><name sortKey="Kolesnikova, L" uniqKey="Kolesnikova L">L. Kolesnikova</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Berger, A" uniqKey="Berger A">A. Berger</name></author><author><name sortKey="Burguiere, A M" uniqKey="Burguiere A">A.M. Burguière</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J. Cinatl</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M. Eickmann</name></author><author><name sortKey="Escriou, N" uniqKey="Escriou N">N. Escriou</name></author><author><name sortKey="Grywna, K" uniqKey="Grywna K">K. Grywna</name></author><author><name sortKey="Kramme, S" uniqKey="Kramme S">S. Kramme</name></author><author><name sortKey="Manuguerra, J C" uniqKey="Manuguerra J">J.C. Manuguerra</name></author><author><name sortKey="Muller, S" uniqKey="Muller S">S. Müller</name></author><author><name sortKey="Rickerts, V" uniqKey="Rickerts V">V. Rickerts</name></author><author><name sortKey="Sturmer, M" uniqKey="Sturmer M">M. Stürmer</name></author><author><name sortKey="Vieth, S" uniqKey="Vieth S">S. Vieth</name></author><author><name sortKey="Klenk, H D" uniqKey="Klenk H">H.D. Klenk</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Schmitz, H" uniqKey="Schmitz H">H. Schmitz</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guan, B J" uniqKey="Guan B">B.J. Guan</name></author><author><name sortKey="Wu, H Y" uniqKey="Wu H">H.Y. Wu</name></author><author><name sortKey="Brian, D A" uniqKey="Brian D">D.A. Brian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gustin, K M" uniqKey="Gustin K">K.M. Gustin</name></author><author><name sortKey="Guan, B J" uniqKey="Guan B">B.J. Guan</name></author><author><name sortKey="Dziduszko, A" uniqKey="Dziduszko A">A. Dziduszko</name></author><author><name sortKey="Brian, D A" uniqKey="Brian D">D.A. Brian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Lokugamage, K G" uniqKey="Lokugamage K">K.G. Lokugamage</name></author><author><name sortKey="Rozovics, J M" uniqKey="Rozovics J">J.M. Rozovics</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Semler, B L" uniqKey="Semler B">B.L. Semler</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Lokugamage, K G" uniqKey="Lokugamage K">K.G. Lokugamage</name></author><author><name sortKey="Rozovics, J M" uniqKey="Rozovics J">J.M. Rozovics</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Semler, B L" uniqKey="Semler B">B.L. Semler</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kamitani, W" uniqKey="Kamitani W">W. Kamitani</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Lokugamage, K G" uniqKey="Lokugamage K">K.G. Lokugamage</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kamitani, W" uniqKey="Kamitani W">W. Kamitani</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Lokugamage, K" uniqKey="Lokugamage K">K. Lokugamage</name></author><author><name sortKey="Ikegami, T" uniqKey="Ikegami T">T. Ikegami</name></author><author><name sortKey="Ito, N" uniqKey="Ito N">N. Ito</name></author><author><name sortKey="Kubo, H" uniqKey="Kubo H">H. Kubo</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Y N" uniqKey="Kim Y">Y.N. Kim</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kindler, E" uniqKey="Kindler E">E. Kindler</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G. Ksiazek</name></author><author><name sortKey="Erdman, D" uniqKey="Erdman D">D. Erdman</name></author><author><name sortKey="Goldsmith, C S" uniqKey="Goldsmith C">C.S. Goldsmith</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R. Zaki</name></author><author><name sortKey="Peret, T" uniqKey="Peret T">T. Peret</name></author><author><name sortKey="Emery, S" uniqKey="Emery S">S. Emery</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author><author><name sortKey="Urbani, C" uniqKey="Urbani C">C. Urbani</name></author><author><name sortKey="Comer, J A" uniqKey="Comer J">J.A. Comer</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Rollin, P E" uniqKey="Rollin P">P.E. Rollin</name></author><author><name sortKey="Dowell, S F" uniqKey="Dowell S">S.F. Dowell</name></author><author><name sortKey="Ling, A E" uniqKey="Ling A">A.E. Ling</name></author><author><name sortKey="Humphrey, C D" uniqKey="Humphrey C">C.D. Humphrey</name></author><author><name sortKey="Shieh, W J" uniqKey="Shieh W">W.J. Shieh</name></author><author><name sortKey="Guarner, J" uniqKey="Guarner J">J. Guarner</name></author><author><name sortKey="Paddock, C D" uniqKey="Paddock C">C.D. Paddock</name></author><author><name sortKey="Rota, P" uniqKey="Rota P">P. Rota</name></author><author><name sortKey="Fields, B" uniqKey="Fields B">B. Fields</name></author><author><name sortKey="Derisi, J" uniqKey="Derisi J">J. DeRisi</name></author><author><name sortKey="Yang, J Y" uniqKey="Yang J">J.Y. Yang</name></author><author><name sortKey="Cox, N" uniqKey="Cox N">N. Cox</name></author><author><name sortKey="Hughes, J M" uniqKey="Hughes J">J.M. Hughes</name></author><author><name sortKey="Leduc, J W" uniqKey="Leduc J">J.W. LeDuc</name></author><author><name sortKey="Bellini, W J" uniqKey="Bellini W">W.J. Bellini</name></author><author><name sortKey="Anderson, L J" uniqKey="Anderson L">L.J. Anderson</name></author><author><name sortKey="Group, S W" uniqKey="Group S">S.W. Group</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lloyd, R E" uniqKey="Lloyd R">R.E. Lloyd</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lokugamage, K G" uniqKey="Lokugamage K">K.G. Lokugamage</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lokugamage, K G" uniqKey="Lokugamage K">K.G. Lokugamage</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Nakagawa, K" uniqKey="Nakagawa K">K. Nakagawa</name></author><author><name sortKey="Terasaki, K" uniqKey="Terasaki K">K. Terasaki</name></author><author><name sortKey="Ramirez, S I" uniqKey="Ramirez S">S.I. Ramirez</name></author><author><name sortKey="Tseng, C T" uniqKey="Tseng C">C.T. Tseng</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Müller</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Jores, J" uniqKey="Jores J">J. Jores</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Younan, M" uniqKey="Younan M">M. Younan</name></author><author><name sortKey="Liljander, A" uniqKey="Liljander A">A. Liljander</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B.J. Bosch</name></author><author><name sortKey="Lattwein, E" uniqKey="Lattwein E">E. Lattwein</name></author><author><name sortKey="Hilali, M" uniqKey="Hilali M">M. Hilali</name></author><author><name sortKey="Musa, B E" uniqKey="Musa B">B.E. Musa</name></author><author><name sortKey="Bornstein, S" uniqKey="Bornstein S">S. Bornstein</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mailles, A" uniqKey="Mailles A">A. Mailles</name></author><author><name sortKey="Blanckaert, K" uniqKey="Blanckaert K">K. Blanckaert</name></author><author><name sortKey="Chaud, P" uniqKey="Chaud P">P. Chaud</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S. van der Werf</name></author><author><name sortKey="Lina, B" uniqKey="Lina B">B. Lina</name></author><author><name sortKey="Caro, V" uniqKey="Caro V">V. Caro</name></author><author><name sortKey="Campese, C" uniqKey="Campese C">C. Campese</name></author><author><name sortKey="Guery, B" uniqKey="Guery B">B. Guéry</name></author><author><name sortKey="Prouvost, H" uniqKey="Prouvost H">H. Prouvost</name></author><author><name sortKey="Lemaire, X" uniqKey="Lemaire X">X. Lemaire</name></author><author><name sortKey="Paty, M C" uniqKey="Paty M">M.C. Paty</name></author><author><name sortKey="Haeghebaert, S" uniqKey="Haeghebaert S">S. Haeghebaert</name></author><author><name sortKey="Antoine, D" uniqKey="Antoine D">D. Antoine</name></author><author><name sortKey="Ettahar, N" uniqKey="Ettahar N">N. Ettahar</name></author><author><name sortKey="Noel, H" uniqKey="Noel H">H. Noel</name></author><author><name sortKey="Behillil, S" uniqKey="Behillil S">S. Behillil</name></author><author><name sortKey="Hendricx, S" uniqKey="Hendricx S">S. Hendricx</name></author><author><name sortKey="Manuguerra, J C" uniqKey="Manuguerra J">J.C. Manuguerra</name></author><author><name sortKey="Enouf, V" uniqKey="Enouf V">V. Enouf</name></author><author><name sortKey="La Ruche, G" uniqKey="La Ruche G">G. La Ruche</name></author><author><name sortKey="Semaille, C" uniqKey="Semaille C">C. Semaille</name></author><author><name sortKey="Coignard, B" uniqKey="Coignard B">B. Coignard</name></author><author><name sortKey="Levy Bruhl, D" uniqKey="Levy Bruhl D">D. Lévy-Bruhl</name></author><author><name sortKey="Weber, F" uniqKey="Weber F">F. Weber</name></author><author><name sortKey="Saura, C" uniqKey="Saura C">C. Saura</name></author><author><name sortKey="Che, D" uniqKey="Che D">D. Che</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Memish, Z A" uniqKey="Memish Z">Z.A. Memish</name></author><author><name sortKey="Cotten, M" uniqKey="Cotten M">M. Cotten</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Watson, S J" uniqKey="Watson S">S.J. Watson</name></author><author><name sortKey="Alsahafi, A J" uniqKey="Alsahafi A">A.J. Alsahafi</name></author><author><name sortKey="Al Rabeeah, A A" uniqKey="Al Rabeeah A">A.A. Al Rabeeah</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Sieberg, A" uniqKey="Sieberg A">A. Sieberg</name></author><author><name sortKey="Makhdoom, H Q" uniqKey="Makhdoom H">H.Q. Makhdoom</name></author><author><name sortKey="Assiri, A" uniqKey="Assiri A">A. Assiri</name></author><author><name sortKey="Al Masri, M" uniqKey="Al Masri M">M. Al Masri</name></author><author><name sortKey="Aldabbagh, S" uniqKey="Aldabbagh S">S. Aldabbagh</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B.J. Bosch</name></author><author><name sortKey="Beer, M" uniqKey="Beer M">M. Beer</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Muller</name></author><author><name sortKey="Kellam, P" uniqKey="Kellam P">P. Kellam</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Lokugamage, K" uniqKey="Lokugamage K">K. Lokugamage</name></author><author><name sortKey="Kamitani, W" uniqKey="Kamitani W">W. Kamitani</name></author><author><name sortKey="Ikegami, T" uniqKey="Ikegami T">T. Ikegami</name></author><author><name sortKey="Tseng, C T" uniqKey="Tseng C">C.T. Tseng</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Ramirez, S I" uniqKey="Ramirez S">S.I. Ramirez</name></author><author><name sortKey="Lokugamage, K G" uniqKey="Lokugamage K">K.G. Lokugamage</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neuman, B W" uniqKey="Neuman B">B.W. Neuman</name></author><author><name sortKey="Chamberlain, P" uniqKey="Chamberlain P">P. Chamberlain</name></author><author><name sortKey="Bowden, F" uniqKey="Bowden F">F. Bowden</name></author><author><name sortKey="Joseph, J" uniqKey="Joseph J">J. Joseph</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perera, R A" uniqKey="Perera R">R.A. Perera</name></author><author><name sortKey="Wang, P" uniqKey="Wang P">P. Wang</name></author><author><name sortKey="Gomaa, M R" uniqKey="Gomaa M">M.R. Gomaa</name></author><author><name sortKey="El Shesheny, R" uniqKey="El Shesheny R">R. El-Shesheny</name></author><author><name sortKey="Kandeil, A" uniqKey="Kandeil A">A. Kandeil</name></author><author><name sortKey="Bagato, O" uniqKey="Bagato O">O. Bagato</name></author><author><name sortKey="Siu, L Y" uniqKey="Siu L">L.Y. Siu</name></author><author><name sortKey="Shehata, M M" uniqKey="Shehata M">M.M. Shehata</name></author><author><name sortKey="Kayed, A S" uniqKey="Kayed A">A.S. Kayed</name></author><author><name sortKey="Moatasim, Y" uniqKey="Moatasim Y">Y. Moatasim</name></author><author><name sortKey="Li, M" uniqKey="Li M">M. Li</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Webby, R J" uniqKey="Webby R">R.J. Webby</name></author><author><name sortKey="Ali, M A" uniqKey="Ali M">M.A. Ali</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Kayali, G" uniqKey="Kayali G">G. Kayali</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Prentice, E" uniqKey="Prentice E">E. Prentice</name></author><author><name sortKey="Mcauliffe, J" uniqKey="Mcauliffe J">J. McAuliffe</name></author><author><name sortKey="Lu, X" uniqKey="Lu X">X. Lu</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author><author><name sortKey="Denison, M R" uniqKey="Denison M">M.R. Denison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raman, S" uniqKey="Raman S">S. Raman</name></author><author><name sortKey="Bouma, P" uniqKey="Bouma P">P. Bouma</name></author><author><name sortKey="Williams, G D" uniqKey="Williams G">G.D. Williams</name></author><author><name sortKey="Brian, D A" uniqKey="Brian D">D.A. Brian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raman, S" uniqKey="Raman S">S. Raman</name></author><author><name sortKey="Brian, D A" uniqKey="Brian D">D.A. Brian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reusken, C B" uniqKey="Reusken C">C.B. Reusken</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B.L. Haagmans</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Müller</name></author><author><name sortKey="Gutierrez, C" uniqKey="Gutierrez C">C. Gutierrez</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.J. Godeke</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Raj, V S" uniqKey="Raj V">V.S. Raj</name></author><author><name sortKey="Smits De Vries, L" uniqKey="Smits De Vries L">L. Smits-De Vries</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S.L. Smits</name></author><author><name sortKey="El Tahir, Y E" uniqKey="El Tahir Y">Y.E. El Tahir</name></author><author><name sortKey="De Sousa, R" uniqKey="De Sousa R">R. De Sousa</name></author><author><name sortKey="Van Beek, J" uniqKey="Van Beek J">J. van Beek</name></author><author><name sortKey="Nowotny, N" uniqKey="Nowotny N">N. Nowotny</name></author><author><name sortKey="Van Maanen, K" uniqKey="Van Maanen K">K. van Maanen</name></author><author><name sortKey="Hidalgo Hermoso, E" uniqKey="Hidalgo Hermoso E">E. Hidalgo-Hermoso</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B.J. Bosch</name></author><author><name sortKey="Rottier, P" uniqKey="Rottier P">P. Rottier</name></author><author><name sortKey="Osterhaus, A" uniqKey="Osterhaus A">A. Osterhaus</name></author><author><name sortKey="Gortazar Schmidt, C" uniqKey="Gortazar Schmidt C">C. Gortázar-Schmidt</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Koopmans, M P" uniqKey="Koopmans M">M.P. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reusken, C B" uniqKey="Reusken C">C.B. Reusken</name></author><author><name sortKey="Messadi, L" uniqKey="Messadi L">L. Messadi</name></author><author><name sortKey="Feyisa, A" uniqKey="Feyisa A">A. Feyisa</name></author><author><name sortKey="Ularamu, H" uniqKey="Ularamu H">H. Ularamu</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.J. Godeke</name></author><author><name sortKey="Danmarwa, A" uniqKey="Danmarwa A">A. Danmarwa</name></author><author><name sortKey="Dawo, F" uniqKey="Dawo F">F. Dawo</name></author><author><name sortKey="Jemli, M" uniqKey="Jemli M">M. Jemli</name></author><author><name sortKey="Melaku, S" uniqKey="Melaku S">S. Melaku</name></author><author><name sortKey="Shamaki, D" uniqKey="Shamaki D">D. Shamaki</name></author><author><name sortKey="Woma, Y" uniqKey="Woma Y">Y. Woma</name></author><author><name sortKey="Wungak, Y" uniqKey="Wungak Y">Y. Wungak</name></author><author><name sortKey="Gebremedhin, E Z" uniqKey="Gebremedhin E">E.Z. Gebremedhin</name></author><author><name sortKey="Zutt, I" uniqKey="Zutt I">I. Zutt</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B.J. Bosch</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B.L. Haagmans</name></author><author><name sortKey="Koopmans, M P" uniqKey="Koopmans M">M.P. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schneider, R J" uniqKey="Schneider R">R.J. Schneider</name></author><author><name sortKey="Mohr, I" uniqKey="Mohr I">I. Mohr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E.J. Snijder</name></author><author><name sortKey="Bredenbeek, P J" uniqKey="Bredenbeek P">P.J. Bredenbeek</name></author><author><name sortKey="Dobbe, J C" uniqKey="Dobbe J">J.C. Dobbe</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Ziebuhr, J" uniqKey="Ziebuhr J">J. Ziebuhr</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Rozanov, M" uniqKey="Rozanov M">M. Rozanov</name></author><author><name sortKey="Spaan, W J" uniqKey="Spaan W">W.J. Spaan</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tamura, K" uniqKey="Tamura K">K. Tamura</name></author><author><name sortKey="Stecher, G" uniqKey="Stecher G">G. Stecher</name></author><author><name sortKey="Peterson, D" uniqKey="Peterson D">D. Peterson</name></author><author><name sortKey="Filipski, A" uniqKey="Filipski A">A. Filipski</name></author><author><name sortKey="Kumar, S" uniqKey="Kumar S">S. Kumar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tanaka, T" uniqKey="Tanaka T">T. Tanaka</name></author><author><name sortKey="Kamitani, W" uniqKey="Kamitani W">W. Kamitani</name></author><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. DeDiego</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author><author><name sortKey="Matsuura, Y" uniqKey="Matsuura Y">Y. Matsuura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Ivanov, K A" uniqKey="Ivanov K">K.A. Ivanov</name></author><author><name sortKey="Putics, A" uniqKey="Putics A">A. Putics</name></author><author><name sortKey="Hertzig, T" uniqKey="Hertzig T">T. Hertzig</name></author><author><name sortKey="Schelle, B" uniqKey="Schelle B">B. Schelle</name></author><author><name sortKey="Bayer, S" uniqKey="Bayer S">S. Bayer</name></author><author><name sortKey="Wei Brich, B" uniqKey="Wei Brich B">B. Weißbrich</name></author><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E.J. Snijder</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H. Rabenau</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="Ziebuhr, J" uniqKey="Ziebuhr J">J. Ziebuhr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tohya, Y" uniqKey="Tohya Y">Y. Tohya</name></author><author><name sortKey="Narayanan, K" uniqKey="Narayanan K">K. Narayanan</name></author><author><name sortKey="Kamitani, W" uniqKey="Kamitani W">W. Kamitani</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Lokugamage, K" uniqKey="Lokugamage K">K. Lokugamage</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="De Graaf, M" uniqKey="De Graaf M">M. de Graaf</name></author><author><name sortKey="Lauber, C" uniqKey="Lauber C">C. Lauber</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T.M. Bestebroer</name></author><author><name sortKey="Raj, V S" uniqKey="Raj V">V.S. Raj</name></author><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A.M. Zaki</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B.L. Haagmans</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E.J. Snijder</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Hoek, L" uniqKey="Van Der Hoek L">L. van der Hoek</name></author><author><name sortKey="Pyrc, K" uniqKey="Pyrc K">K. Pyrc</name></author><author><name sortKey="Berkhout, B" uniqKey="Berkhout B">B. Berkhout</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Hoek, L" uniqKey="Van Der Hoek L">L. van der Hoek</name></author><author><name sortKey="Pyrc, K" uniqKey="Pyrc K">K. Pyrc</name></author><author><name sortKey="Jebbink, M F" uniqKey="Jebbink M">M.F. Jebbink</name></author><author><name sortKey="Vermeulen Oost, W" uniqKey="Vermeulen Oost W">W. Vermeulen-Oost</name></author><author><name sortKey="Berkhout, R J" uniqKey="Berkhout R">R.J. Berkhout</name></author><author><name sortKey="Wolthers, K C" uniqKey="Wolthers K">K.C. Wolthers</name></author><author><name sortKey="Wertheim Van Dillen, P M" uniqKey="Wertheim Van Dillen P">P.M. Wertheim-van Dillen</name></author><author><name sortKey="Kaandorp, J" uniqKey="Kaandorp J">J. Kaandorp</name></author><author><name sortKey="Spaargaren, J" uniqKey="Spaargaren J">J. Spaargaren</name></author><author><name sortKey="Berkhout, B" uniqKey="Berkhout B">B. Berkhout</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Shi, H" uniqKey="Shi H">H. Shi</name></author><author><name sortKey="Rigolet, P" uniqKey="Rigolet P">P. Rigolet</name></author><author><name sortKey="Wu, N" uniqKey="Wu N">N. Wu</name></author><author><name sortKey="Zhu, L" uniqKey="Zhu L">L. Zhu</name></author><author><name sortKey="Xi, X G" uniqKey="Xi X">X.G. Xi</name></author><author><name sortKey="Vabret, A" uniqKey="Vabret A">A. Vabret</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Wang, T" uniqKey="Wang T">T. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wathelet, M G" uniqKey="Wathelet M">M.G. Wathelet</name></author><author><name sortKey="Orr, M" uniqKey="Orr M">M. Orr</name></author><author><name sortKey="Frieman, M B" uniqKey="Frieman M">M.B. Frieman</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weiss, S R" uniqKey="Weiss S">S.R. Weiss</name></author><author><name sortKey="Navas Martin, S" uniqKey="Navas Martin S">S. Navas-Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Cai, J J" uniqKey="Cai J">J.J. Cai</name></author><author><name sortKey="Luk, W K" uniqKey="Luk W">W.K. Luk</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamshchikov, V" uniqKey="Yamshchikov V">V. Yamshchikov</name></author><author><name sortKey="Mishin, V" uniqKey="Mishin V">V. Mishin</name></author><author><name sortKey="Cominelli, F" uniqKey="Cominelli F">F. Cominelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, D" uniqKey="Yang D">D. Yang</name></author><author><name sortKey="Leibowitz, J L" uniqKey="Leibowitz J">J.L. Leibowitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Curtis, K M" uniqKey="Curtis K">K.M. Curtis</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zust, R" uniqKey="Zust R">R. Züst</name></author><author><name sortKey="Cervantes Barragan, L" uniqKey="Cervantes Barragan L">L. Cervantes-Barragán</name></author><author><name sortKey="Kuri, T" uniqKey="Kuri T">T. Kuri</name></author><author><name sortKey="Blakqori, G" uniqKey="Blakqori G">G. Blakqori</name></author><author><name sortKey="Weber, F" uniqKey="Weber F">F. Weber</name></author><author><name sortKey="Ludewig, B" uniqKey="Ludewig B">B. Ludewig</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A.M. Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T.M. Bestebroer</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zuker, M" uniqKey="Zuker M">M. Zuker</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Terada, Yutaka" sort="Terada, Yutaka" uniqKey="Terada Y" first="Yutaka" last="Terada">Yutaka Terada</name></noRegion><name sortKey="Kamitani, Wataru" sort="Kamitani, Wataru" uniqKey="Kamitani W" first="Wataru" last="Kamitani">Wataru Kamitani</name><name sortKey="Kamitani, Wataru" sort="Kamitani, Wataru" uniqKey="Kamitani W" first="Wataru" last="Kamitani">Wataru Kamitani</name><name sortKey="Kawachi, Kengo" sort="Kawachi, Kengo" uniqKey="Kawachi K" first="Kengo" last="Kawachi">Kengo Kawachi</name><name sortKey="Kawachi, Kengo" sort="Kawachi, Kengo" uniqKey="Kawachi K" first="Kengo" last="Kawachi">Kengo Kawachi</name><name sortKey="Matsuura, Yoshiharu" sort="Matsuura, Yoshiharu" uniqKey="Matsuura Y" first="Yoshiharu" last="Matsuura">Yoshiharu Matsuura</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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